Intelligent Health.tech Issue 29 | Page 63

D I G I T A L D I A G N O S T I C S

Leading epigenetic therapy company Tune Therapeutics will begin a clinical trial in Hong Kong after receiving a Certificate for Clinical Trial from the Hong Kong Department of Health .

This marks the second global approval to commence a Phase 1b clinical trial for Tune-401 , an investigational epigenetic silencing therapy designed to treat chronic hepatitis B ( CHB ).
“ We ’ re taking a fresh angle on the battle against chronic hepatitis B ,” said Derek Jantz , Chief Scientific Officer , Tune Therapeutics .
“ Current standard-of-care treatments are rarely curative due to the virus mechanism of infection . But by employing epigenetic silencing to target both integrated viral DNA and cccDNA , we are replicating the natural processes observed in spontaneous functional cure and aiming to make that outcome the norm in HBV treatment .”
The company ’ s leading therapeutic candidate , Tune-401 , has now been approved for clinical trials in both Hong Kong and New Zealand .

TUNE THERAPEUTICS RECEIVES APPROVAL TO INITIATE CLINICAL TRIAL IN HONG KONG FOR HEPB EPIGENETIC SILENCER

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