S C R U B B I N G U P
Medical implants and biomedical devices often cause inflammatory responses due to poor biocompatibility . Apatite coatings offer a potential solution but limited cell adhesion is often a challenge . To address this , scientists developed advanced apatite nanoparticles for implant coatings with superior cell adhesion . By adjusting pH during synthesis of nanoparticles , they enhanced the surface properties of these nanoparticles , achieving improved water interactions and greater structural stability , paving the way for more effective and biocompatible medical implants .
INNOVATIVE APATITE NANOPARTICLES FOR ADVANCING THE BIOCOMPATIBILITY OF IMPLANTED BIODEVICES
Medical implants have transformed healthcare , offering innovative solutions with advanced materials and technologies . However , many biomedical devices face challenges like insufficient cell adhesion , leading to inflammatory responses after their implantation in the body . Apatite coatings , particularly hydroxyapatite ( HA ), a naturally occurring form of apatite found in bones , have been shown to promote better integration with surrounding tissues . However , the biocompatibility of artificially synthesized apatite nanoparticles often falls short of expectations , primarily due to the nanoparticles ’ limited ability to bind effectively with biological tissues .
To overcome this challenge , researchers at Nagaoka University of Technology , Japan , have developed a method for synthesizing surface-modified apatite nanoparticles that results in improved cell adhesion , offering new possibilities for the next generation of biocompatible medical implants . Led by Dr Motohiro Tagaya , Associate Professor at the Department of Materials Science and Bioengineering at Nagaoka University of Technology , Japan , this research aims to enhance the performance of apatite coatings and advance the field of biocompatible materials for medical devices . The findings of this study were published online in ACS Applied Materials & Interfaces , on January 13 , 2025 , and in Volume 17 , Issue 4 of the journal on January 29 , 2025 . Along with Dr Tagaya , Mr Kazuto Sugimoto from Nagaoka University of Technology , Dr Tania Guadalupe Peñaflor Galindo from Sophia University , and Mr Ryota Akutsu from Nagaoka University of Technology were also a part of this research team .
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